128030-40-0

Upstream product

• 613-94-5 benzoic acid hydrazide 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 825-56-9 2-phenyl-1,3,4-oxadiazole 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 487-68-3 mesytaldehyde 

Downstream Products

• 290827-08-6 1,2-dihydro-3-phenyl-6-(2,4,6-trimethylphenyl)tetrazine 

Relevant academic research and scientific papers

Spectral luminescent properties of 2-aryl-5-(2,4,6-trimethylphenyl)-1Н-1,3,4-oxadiazoles

Reaction of aroylhydrazides with 2,4,6-trimethylbenzoyl chloride in the presence of Et3N afforded N-(mesityl)aroylhydrazides, which through subsequent cyclization at treatment with SOCl2 resulted in 2-aryl-5-(2,4,6-trimethylphenyl)-1Н-1,3,4-oxadiazoles. For 2-hydroxyphenyl derivative containing a stable O–H N intramolecular bond a low quantum luminescence yield is observed (φ 0.006–0.038) due to the nonradiative deactivation of the agitated state by ESPIT mechanism.

C-H arylation of azaheterocycles: A direct ligand-free and Cu-catalyzed approach using diaryliodonium salts

An efficient and high yielding Cu-catalyzed direct C-H arylation of azaheterocycles including oxadiazoles, thiadiazoles, benzoxazoles and benzothiazoles has been achieved by employing easily accessible diaryliodonium salts. the Partner Organisations 2014.

I2-mediated oxidative C-O bond formation for the synthesis of 1,3,4-oxadiazoles from aldehydes and hydrazides

A practical and transition-metal-free oxidative cyclization of acylhydrazones into 1,3,4-oxadiazoles has been developed by employing stoichiometric molecular iodine in the presence of potassium carbonate. The conditions of this cyclization reaction also work well with crude acylhydrazone substrates obtained from the condensation of aldehydes and hydrazides. A series of symmetrical and asymmetrical 2,5-disubstituted (aryl, alkyl, and/or vinyl) 1,3,4-oxadiazoles can be conveniently generated in an efficient and scalable fashion.

Steric effects on the regioselectivity in two-step Diels-Alder reactions of 1,2,4,5-tetrazines with 2-cyclopropylidene-4,5-dihydro-1,3-dimethyl- imidazolidine

The regioselectivity of the two-step Diels-Alder reaction of unsymmetrically substituted tetrazines 4 with 2-cyclopropylidene- imidazolidine 6 is investigated. The first reversible step of the cycloaddition affording zwitterions 7 and 8 is controlled by s