128039-93-0

Upstream product

• 38970-47-7 2-(2-methylenecyclohexyl)acetic acid 
• 53544-45-9 ethyl (2-methylidenylcyclohexyl)acetate 
• 62-53-3 aniline 
• 103-71-9 phenyl isocyanate 
• 3710-30-3 1,7-Octadiene 

Relevant academic research and scientific papers

Pd(II)-catalyzed intramolecular amidoarylation of alkenes with molecular oxygen as sole oxidant

Stereoselective palladium-catalyzed synthesis of structurally versatile indoline derivatives, using molecular oxygen as the sole oxidant, is described. New C-N and C-C bonds form across an alkene in an intramolecular manner. The C-N bond-forming step proceeds via a syn-amidopalladation pathway. The moderate kinetic isotope effects (intramolecular KIE = 3.56) suggest that electrophilic aromatic substitution occurs in the arylation step.

Ligandgesteuerte Produktbildung bei Umsetzung von 1,7-Octadien mit Phenylisocyanat an Nickel(0)

1,7-Octadiene and phenylisocyanate react with the (Lig)Ni0-system, depending on the ligand, to give differing products.Thus with tricyclohexylphosphane the reaction is accompanied by cyclization and (2-methylenecyclohexyl)acetanilide(V) is formed.On the other hand, reaction with the weakly basic tricyclohexylphosphite gives the acyclic nona-2,8-dienecarboxanilide (VI).