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128053-01-0

(2S,3S)-N-benzyl-3-hydroxyleucine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 128053-01-0 Structure

  • Basic information

    1. Product Name: (2S,3S)-N-benzyl-3-hydroxyleucine
    2. Synonyms: (2S,3S)-N-benzyl-3-hydroxyleucine
    3. CAS NO:128053-01-0
    4. Molecular Formula:
    5. Molecular Weight: 237.299
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 128053-01-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2S,3S)-N-benzyl-3-hydroxyleucine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2S,3S)-N-benzyl-3-hydroxyleucine(128053-01-0)
    11. EPA Substance Registry System: (2S,3S)-N-benzyl-3-hydroxyleucine(128053-01-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 128053-01-0(Hazardous Substances Data)

128053-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 128053-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,0,5 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 128053-01:
(8*1)+(7*2)+(6*8)+(5*0)+(4*5)+(3*3)+(2*0)+(1*1)=100
100 % 10 = 0
So 128053-01-0 is a valid CAS Registry Number.

128053-01-0Relevant articles and documents

Total synthesis of (+)-lactacystin

Nagamitsu, Tohru,Sunazuka, Toshiaki,Tanaka, Haruo,Omura, Satoshi,Sprengeler, Paul A.,Smith III, Amos B.

, p. 3584 - 3590 (2007/10/03)

A total synthesis of the novel neurotrophic agent (+)-lactacystin (1) has been achieved in 11 steps and 14% overall yield from (2R,3S)-3-hydroxyleucine [(+)-16]. The construction and bioassay of several active analogs are also described. A new asymmetric approach furnished the four stereoisomers of 3-hydroxyleucine, as required starting materials in high overall yield and enantiomeric purity.

An efficient asymmetric synthesis of the four stereoisomers of 3-hydroxyleucine

Sunazuka, Toshiaki,Nagamitsu, Tohru,Tanaka, Haruo,Omura, Satoshi,Sprengeler, Paul A.,Smith III, Amos B.

, p. 4447 - 4448 (2007/10/02)

The four stereoisomers of 3-hydroxyleucine have been prepared in high overall yield and enantiomeric purity. Key steps include Sharpless asymmetric epoxidation, benzyl isocyanate-induced epoxide opening, and epimerization of an intermediate oxazolidinone ester.

An enantioselective synthesis of (2S,3S)- and (2R,3S)-3-hydroxyleucine

Correy,Lee, Duck-Hyung,Choi, Soongyu

, p. 6735 - 6738 (2007/10/02)

α-Bromo β-hydroxy ester 2 was prepared in a preparative scale by a 96 : 4 enantioselective aldol reaction of t-butyl bromoacetate with isobutyraldehyde and converted efficiently to either (2S,3S)-or (2R,3S)-3-hydroxyleucine (7 or 11).

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