1280709-98-9Relevant academic research and scientific papers
Enantioselective direct vinylogous michael addition of functionalized furanones to nitroalkenes catalyzed by an axially chiral guanidine base
Terada, Masahiro,Ando, Kenichi
, p. 2026 - 2029 (2011/06/23)
The highly syn-diastereo- and enantioselective direct vinylogous Michael addition ofα-thio substituted furanones with conjugate nitroalkenes was demonstrated using an axially chiral guanidine base catalyst. The method provides facile access to enantioenriched α,γ-functionalized butenolides that can be further manipulated, thereby rendering them useful synthetic intermediates. 2011 American Chemical Society.
