1280725-57-6Relevant articles and documents
Tandem aldol condensation/platinacycle-catalyzed addition reactions of aldehydes, methyl ketones, and arylboronic acids
Liao, Yuan-Xi,Hu, Qiao-Sheng
supporting information, p. 5897 - 5901,5 (2020/09/02)
Aldol condensation of aldehydes with methyl ketones followed by anionic four-electron donor-based (type I) platinacycle-catalyzed addition reactions of arylboronic acids to form β-arylated ketones is described. Good to excellent yields of β-arylated ketones were obtained for the tandem reactions of aromatic/aliphatic aldehydes, methyl ketones, and arylboronic acids, and moderate yields were observed for the tandem reactions of α,β-unsaturated aldehydes. The aldol condensation of aldehydes with methyl ketones was successfully combined with the platinacycle-catalyzed addition reactions of arylboronic acids in a tandem fashion. A variety of β-arylated ketones was obtained in good to excellent yields.