128100-13-0

Basic information

• Product Name: Benzenesulfonyl-acetic acid (2S,3R)-3-benzyloxymethyl-oxiranylmethyl ester
• CAS NO: 128100-13-0
• Molecular Weight: 376.43
• Mol File: 128100-13-0.mol

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl-acetic acid (2S,3R)-3-benzyloxymethyl-oxiranylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl-acetic acid (2S,3R)-3-benzyloxymethyl-oxiranylmethyl ester(128100-13-0)
• EPA Substance Registry System: Benzenesulfonyl-acetic acid (2S,3R)-3-benzyloxymethyl-oxiranylmethyl ester(128100-13-0)

Safety Data

• Hazardous Substances Data: 128100-13-0(Hazardous Substances Data)

Upstream product

• 3959-23-7 benzenesulfonylacetic acid 
• 78513-07-2 ((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)methanol 
• 87172-27-8 cis-4-benzyloxy-2,3-epoxy-1-butanol 

Downstream Products

• 128100-24-3 (1R,5S,6R)-1-Benzenesulfonyl-6-benzyloxymethyl-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 128100-14-1 (3S,4S)-3-Benzenesulfonyl-4-((R)-2-benzyloxy-1-hydroxy-ethyl)-dihydro-furan-2-one 
• 84621-89-6 trans-4-(benzyloxy)-2,3-epoxy-1-butanol 
• 128100-14-1 (3S,4S)-3-Benzenesulfonyl-4-((S)-2-benzyloxy-1-hydroxy-ethyl)-dihydro-furan-2-one 
• 131685-49-9 (Z)-(2R,3R)-1-Benzyloxy-3-methyl-hept-5-en-2-ol 
• 128100-26-5 (4S,5R)-5-Benzyloxymethyl-4-hydroxymethyl-dihydro-furan-2-one 
• 131685-49-9 (2R,3R,5E)-1-(benzyloxy)-3-methyl-5-hepten-2-ol 
• 131685-48-8 (4R,5R)-5-Benzyloxymethyl-4-methyl-tetrahydro-furan-2-ol 
• 128100-14-1 (3S,4S)-3-Benzenesulfonyl-4-((R)-2-benzyloxy-1-hydroxy-ethyl)-dihydro-furan-2-one 

Relevant articles and documents

Cyclofunctionalisation of epoxyalcohol derivatives. 4. Cyclisation of sulfonylacetate dianions: A synthesis of 'MeBMT'.

α,α-Dianions, derived from arenesulfonylacetate esters of 2,3-epoxyalcohols, cyclised to give 3-arenesulfonyl-4-(1-hydroxyalkyl)-γ-butyrolactones. Dianion fragmentation to regenerate the epoxyalcohol was a competing, substrate-dependent process. Sulfonylactone (9) was elaborated efficiently to an advanced intermediate for the unusual aminoacid 'MeBMT' (5), and also to stereodefined cyclopropane derivatives.