131685-48-8

Upstream product

• 131685-47-7 (2RS,4R,5R)-5-<(benzyloxy)methyl>-2-ethoxy-4-methyltetrahydrofuran 
• 128100-14-1 (3S,4S)-3-Benzenesulfonyl-4-((R)-2-benzyloxy-1-hydroxy-ethyl)-dihydro-furan-2-one 
• 93553-66-3 (2R)-1-(benzyloxy)but-3-en-2-ol 
• 1032746-45-4 C₁₃H₁₇NO₂ 
• 131685-46-6 [(R)-2-(2-Bromo-1-ethoxy-ethoxy)-but-3-enyloxymethyl]-benzene 
• 128100-13-0 Benzenesulfonyl-acetic acid (2R,3S)-3-benzyloxymethyl-oxiranylmethyl ester 
• 78513-07-2 ((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)methanol 
• 128100-26-5 (4S,5R)-5-Benzyloxymethyl-4-hydroxymethyl-dihydro-furan-2-one 

Downstream Products

• 131685-49-9 (2R,3R,5E)-1-(benzyloxy)-3-methyl-5-hepten-2-ol 
• 131685-49-9 (Z)-(2R,3R)-1-Benzyloxy-3-methyl-hept-5-en-2-ol 
• 81135-51-5 [(E)-(2R,3R)-2-(2-Ethoxy-ethoxy)-3-methyl-hept-5-enyloxymethyl]-benzene 
• 1032746-46-5 (2R,3R)-1-(benzyloxy)-3-methylhex-5-en-2-ol 

Relevant academic research and scientific papers

An efficient strategy for the synthesis of endocyclic enol ethers and its application to the synthesis of spiroacetals

(Chemical Equation Presented) An efficient strategy for the synthesis of endocyclic enol ethers based on a Suzuki-Miyaura coupling/ring-closing metathesis sequence has been developed. The strategy has successfully been applied to the synthesis of spiroacetals, including cytotoxic marine metabolites attenols A and B.

Cyclofunctionalisation of epoxyalcohol derivatives. 4. Cyclisation of sulfonylacetate dianions: A synthesis of 'MeBMT'.

α,α-Dianions, derived from arenesulfonylacetate esters of 2,3-epoxyalcohols, cyclised to give 3-arenesulfonyl-4-(1-hydroxyalkyl)-γ-butyrolactones. Dianion fragmentation to regenerate the epoxyalcohol was a competing, substrate-dependent process. Sulfonylactone (9) was elaborated efficiently to an advanced intermediate for the unusual aminoacid 'MeBMT' (5), and also to stereodefined cyclopropane derivatives.