128103-11-7Relevant articles and documents
Palladium-Catalyzed Cascade Approach to 12-(Aryl)indolo[1,2- c ]quinazolin-6(5 H)-ones
Arcadi, Antonio,Cacchi, Sandro,Fabrizi, Giancarlo,Ghirga, Francesca,Goggiamani, Antonella,Iazzetti, Antonia,Marinelli, Fabio
, p. 1133 - 1140 (2018)
A straightforward one-pot approach to the synthesis of challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones is described. Starting from readily available o -(o -aminophenylethynyl)trifluoroacetanilides, palladium-catalyzed aminoarylation of the triple bond with ArI, ArBr, and ArN 2+ BF 4- is followed by cyclization of the resulting N -trifluoroacetyl-2-(o -aminophenyl)-3-aryl indole. This sequential reaction provides the title compounds by means of a rare elimination of trifluoromethane.
Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones
Arcadi, Antonio,Cacchi, Sandro,Fabrizi, Giancarlo,Fochetti, Andrea,Ghirga, Francesca,Goggiamani, Antonella,Iazzetti, Antonia,Marinelli, Fabio
, p. 3287 - 3294 (2019/08/28)
A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.
New methodology for the preparation of pyrrole and indole derivatives via iminophosphoranes:synthesis of pyrrolo[1,2-a]quinoxalines, indolo[3,2-c]quinolines and indolo[1,2-c]quinazolines
Molina, Pedro,Alajarin, Mateo,Vidal, Angel
, p. 1063 - 1078 (2007/10/02)
The aza-Wittig reaction of iminophosphorane N-[o-(triphenylphosphoranylidene)amino]-phenyl pyrrole 4 with heterocumulenes leads to functionalized pyrrolo[1,2-a]quinoxalines. Iminophosphorane 19, derived from 2-(o-amino)phenyl indole, reacts under mild con