128164-69-2Relevant academic research and scientific papers
Rearrangements of Bridgehead Bromides. A Direct Synthesis of epi-Modhephene
Kraus, George A.,Shi, Jianmin
, p. 5423 - 5424 (1990)
The reaction of nucleophiles with bridgehead bromides 3 and 4 affords rearrangement products resulting from addition of the nucleophile to the carbonyl group followed by ring contraction.This rearrangement has been employed in a direct synthesis of epi-mo
Reactions of Bridgehead Halides. A Synthesis of Modhephene, Isomodhephene, and epi-Modhephene
Kraus, George A.,Shi, Jianmin
, p. 4147 - 4151 (2007/10/02)
A synthesis of modhephene has been achieved, the key feature of which is the use of a novel nucleophilic addition/rearrangement reaction to develop the carbon framework.Stereochemical control of the stereogenic center bearing the methyl group was accompli
