128175-89-3

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 63792-78-9 D-Leu-Phe-D-Leu-Phe-OMe 
• 63792-75-6 D-Leu-Phe-OMe 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 128175-90-6 Boc-D-Leu-Phe-D-Leu-Phe-OMe 
• 37885-98-6 H-DLeu-Phe-OMe*HCl 
• 92463-61-1 Boc-D-Leu-Phe-OH 
• 87976-66-7 Boc-D-Leu-Phe-OMe 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 16937-99-8 N-Boc-D-Leu 

Downstream Products

• 66556-73-8 Boc-FL(D)FL(D)F 
• 242148-29-4 isopropylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 242148-26-1 p-tolylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 242148-24-9 m-tolylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 242148-28-3 3',5'-dimethylphenyl-ureido-(Phe-D-Leu)₂-Phe-OMe 

Relevant academic research and scientific papers

Conformational aspects of human formylpeptide receptor antagonists

The conformation of several Phe-D-Leu-Phe-D-Leu-Phe analogues was analyzed using infrared absorption and circular dichroism. Their effect on human neutrophils was verified by receptor binding and chemotaxis assays. The results demonstrate that the compounds examined prefer an ordered conformation (β-turn) in amphipatic environment, and that they are able to antagonize the neutrophil functions evoked by CHO-Met-Leu-Phe.