63792-75-6

Basic information

• Product Name: L-Phenylalanine, N-D-leucyl-, methyl ester
• CAS NO: 63792-75-6
• Molecular Formula: C16H24N2O3
• Molecular Weight: 292.378
• Mol File: 63792-75-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-D-leucyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-D-leucyl-, methyl ester(63792-75-6)
• EPA Substance Registry System: L-Phenylalanine, N-D-leucyl-, methyl ester(63792-75-6)

Safety Data

• Hazardous Substances Data: 63792-75-6(Hazardous Substances Data)

Upstream product

• 87976-66-7 Boc-D-Leu-Phe-OMe 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 16937-99-8 N-Boc-D-Leu 

Downstream Products

• 1006104-48-8 C₂₆H₄₁N₃O₆ 
• 242148-28-3 3',5'-dimethylphenyl-ureido-(Phe-D-Leu)₂-Phe-OMe 
• 242148-24-9 m-tolylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 242148-26-1 p-tolylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 66556-73-8 Boc-FL(D)FL(D)F 
• 128175-89-3 Boc-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 242148-29-4 isopropylureido-Phe-D-Leu-Phe-D-Leu-Phe-OMe 
• 63792-78-9 D-Leu-Phe-D-Leu-Phe-OMe 
• 909108-60-7 (S)-2-((R)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid 
• 909108-59-4 (S)-2-((R)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid methyl ester 
• 951005-64-4 (S)-2-[(R)-2-((S)-2-Amino-3-methyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 
• 934715-41-0 2-(2-{2-[2-(2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-butyrylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid methyl ester 
• 934715-78-3 2-(2-{2-[2-(2-amino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-butyrylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid 
• 934715-40-9 2-[2-(2-amino-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines

We report an extensive structure-activity relationship (SAR) of 62 compounds active against two drug-resistant colon cancer cell lines. Our comprehensive evaluation of two generations of compounds utilizes SAR, NMR, and molecular modeling to evaluate the

Synthesis of second-generation Sansalvamide A derivatives: Novel templates as potential antitumor agents

We report the synthesis of 34 second-generation Sansalvamide A derivatives. San A derivatives have unique anticancer properties and target multiple cancers, including colon, pancreatic, breast, prostate, and melanoma. As novel templates, the derivatives d

High-yielding macrocyclization conditions used in the synthesis of novel Sansalvamide A derivatives

Described are the syntheses of nine Sansalvamide A derivatives using new, high-yielding, in situ deprotection-cyclization conditions that are general for this series of macrocycles, 55% average for both steps. This is 10-fold greater than previously repor