1281850-60-9

Upstream product

• 768-70-7 1-ethynyl-3-methoxybenzene 
• 104-94-9 4-methoxy-aniline 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 

Downstream Products

• 148717-49-1 tecalcet 
• 177172-48-4 (R)-3-(2-chlorophenyl)-N-(1-(3'-methoxyphenyl)ethyl)propanamide 
• 88196-70-7 (R)-1-(3-methoxyphenyl)ethylamine 
• 1157860-53-1 N-(p-methoxyphenyl)-1-(m-methoxyphenyl)ethylamine 
• 1448068-00-5 C₂₆H₃₁ClIrNO₂ 
• 1281850-68-7 N-{1-(2-n-hexyl-5-methoxyphenyl)ethyl}-4-methoxyaniline 
• 1281850-69-8 N-{1-(2-n-hexyl-3-methoxyphenyl)ethyl}-4-methoxyaniline 

Relevant academic research and scientific papers

Oxidative Kinetic Resolution of Acyclic Amines Based on Equilibrium Control

An oxidative kinetic resolution of racemic acyclic amines was developed using an imine derivative as the resolving reagent and chiral phosphoric acid as the catalyst to give enantiomers in good yields with high to excellent enantioselectivities. The key t

HΒ Catalyzed Condensation Reaction Between Aromatic Ketones and Anilines: To Access Ketimines (Imines)

Abstract: A simple approach for the formation of imines by condensation of ketones and anilines over heterogeneous catalyst (Hβ zeolite) has been successfully developed. The present catalytic system scope was explored for various aromatic ketones and anil

Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines

A new type of chiral sulfinamide phosphinate catalysts with up to three stereogenic centers, readily accessible from commercially available starting materials, is reported. The naphthyl derivative SulPhos proved to be highly efficient in the organocatalyt

Primary amines by transfer hydrogenative reductive amination of ketones by using cyclometalated IrIII catalysts

Cyclometalated iridium complexes are found to be versatile catalysts for the direct reductive amination (DRA) of carbonyls to give primary amines under transfer-hydrogenation conditions with ammonium formate as both the nitrogen and hydrogen source. These complexes are easy to synthesise and their ligands can be easily tuned. The activity and chemoselectivity of the catalyst towards primary amines is excellent, with a substrate to catalyst ratio (S/C) of 1000 being feasible. Both aromatic and aliphatic primary amines were obtained in high yields. Moreover, a first example of homogeneously catalysed transfer-hydrogenative DRA has been realised for β-keto ethers, leading to the corresponding β-amino ethers. In addition, non-natural α-amino acids could also be obtained in excellent yields with this method. Reduce the work! A broad range of ketones have been successfully aminated to afford primary amines under transfer-hydrogenation conditions by using ammonium formate as the amine source and 0.1 mol % of a cyclometalated IrIII catalyst (see scheme). Copyright

Robust cyclometallated Ir(iii) catalysts for the homogeneous hydrogenation of N-heterocycles under mild conditions

Cyclometallated Cp*Ir(N∧C)Cl complexes derived from N-aryl ketimines are highly active catalysts for the reduction of N-heterocycles under ambient conditions and 1 atm H2 pressure. The reaction tolerates a broad range of other potentially reducible functionalities and does not require the use of specialised equipment, additives or purified solvent.

Highly enantioselective imine hydrogenation catalyzed by ruthenium phosphane-phosphite diamine complexes

Mildly does it: A highly enantioselective catalyst for the hydrogenation of N-aryl imines is described (see scheme). This catalyst offers practical advantages because it operates under very mild conditions and is based on an Ru complex with a diamine as t

Rhodium(III)-catalyzed hydroamination of aromatic terminal alkynes with anilines

The dinuclear Rh(III) species [Cp*RhCl2]2 catalyzes the hydroamination reaction between an aromatic terminal alkyne (ArCCH) and an aniline (Ar′NH2), in the presence of a salt additive, to afford the ketimine Ar′N=C(Me)(Ar). A reaction pathway has been proposed on the basis of experimental and computational studies.