1281860-91-0Relevant academic research and scientific papers
Rapid access to cis-cyclobutane γ-amino acids in enantiomerically pure form
André, Virginie,Vidal, Anne,Ollivier, Jean,Robin, Sylvie,Aitken, David J.
, p. 1253 - 1255 (2011)
The (+)-(1R,2S) and (-)-(1S,2R) stereoisomers of 2-(aminomethyl) cyclobutane-1-carboxylic acid have been prepared using a short and efficient strategy, which employs the photochemical [2+2] cycloaddition reaction between ethylene and an unsaturated γ-lactam as the key step.
A unified synthesis of all stereoisomers of 2-(aminomethyl)cyclobutane-1- carboxylic acid
André, Virginie,Gras, Marjolaine,Awada, Hawraà,Guillot, Régis,Robin, Sylvie,Aitken, David J.
, p. 3571 - 3576 (2013/05/09)
All four stereoisomers of 2-(aminomethyl)cyclobutane-1-carboxylic acid have been prepared starting from a single chirally derivatized unsaturated γ-lactam. A photochemical [2+2] cycloaddition reaction of this compound with ethylene was employed to create
