1281881-52-4Relevant academic research and scientific papers
A novel series of homoallylic amines as potential antimicrobials
Rai, U. Sankappa,Isloor, Arun M.,Shetty, Prakash,Isloor, Nishitha,Padaki, Mahesh,Fun, Hoong-Kun
, p. 1090 - 1097 (2012)
An efficient catalytic three-component reaction of aldehydes, amines, and allyltributylstannate has been successfully developed to produce homoallylic amines at 25°C, in excellent yields, in the presence of 1 mol% of trifluoroacetic acid an inexpensive and environmentally friendly catalyst. Newly synthesized compounds were confirmed by spectral studies. Compound 3o was characterized by single crystal X-ray analysis. All the compounds were also screened for their antimicrobial activity. Halogen-substituted compounds namely 3d, 3g, 3n, and 3o have showed excellent antibacterial activity. Springer Science+Business Media, LLC 2011.
