Medicinal Chemistry Research p. 1090 - 1097 (2012)
Update date:2022-07-31
Topics:
Rai, U. Sankappa
Isloor, Arun M.
Shetty, Prakash
Isloor, Nishitha
Padaki, Mahesh
Fun, Hoong-Kun
An efficient catalytic three-component reaction of aldehydes, amines, and allyltributylstannate has been successfully developed to produce homoallylic amines at 25°C, in excellent yields, in the presence of 1 mol% of trifluoroacetic acid an inexpensive and environmentally friendly catalyst. Newly synthesized compounds were confirmed by spectral studies. Compound 3o was characterized by single crystal X-ray analysis. All the compounds were also screened for their antimicrobial activity. Halogen-substituted compounds namely 3d, 3g, 3n, and 3o have showed excellent antibacterial activity. Springer Science+Business Media, LLC 2011.
View MoreContact:+91 - 22 - 26355700
Address:17, Lotus Business Park, Andheri West
Contact:+86-913-2223392
Address:No. 32, Xinanjing Road, Weinan City, Shaanxi Province, 714000, China
Yancheng Creator Chemical Co., Ltd
Contact:0086-515-88710008 88710068 88710858 88710868
Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Contact:+86-21-56338808
Address:799 Dunhuang Road, Putuo
Xiamen Goodhealth Pharmchem Co., Ltd.
Contact:0086-592-2097683
Address:404R No.2 54# Minzu Rd., Xiamen, China
Doi:10.1134/S0022476613030050
(2013)Doi:10.1016/S0040-4020(01)00247-2
(2001)Doi:10.1139/V06-184
(2007)Doi:10.1039/c0cc02941f
(2010)Doi:10.1002/hlca.19710540852
(1971)Doi:10.1021/ja0042682
(2001)