1281895-48-4

Upstream product

• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 870-50-8 di-tert-butyl-diazodicarboxylate 
• 1281895-12-2 pentan-3-yl 3-(3,4-dimethoxyphenyl)-2-methyl-3-oxopropanoate 
• 1061631-11-5 pentan-3-yl 3-(3,4-dimethoxyphenyl)-3-oxopropanoate 
• 74053-93-3 methyl 3-(3,4-dimethoxyphenyl)-3-oxopropionate 

Downstream Products

• 1281895-86-0 (S)-benzyl 2-(1-(3,4-dimethoxyphenyl)-3-(pentan-3-yloxy)-2-methyl-1,3-dioxopropan-2-yl)hydrazinecarboxylate 
• 1281895-88-2 (S)-benzyl 2-(3-(3,4-dimethoxyphenyl)-1-(pentan-3-yloxy)-2-methyl-1-oxopropan-2-yl)hydrazinecarboxylate 

Relevant academic research and scientific papers

Fluorous l -Carbidopa Precursors: Highly Enantioselective Synthesis and Computational Prediction of Bioactivity

New fluorous enantiopure (S)-α-aminated β-keto esters were prepared through a highly enantioselective electrophilic α-amination step in the presence of europium triflate and (R,R)-phenyl-pybox. These compounds are precursors of fluorinated analogues of l-

Asymmetric Synthesis of L-carbidopa based on a highly enantioselective α-amination

A stereoselective synthesis of l-carbidopa in seven steps and 50% overall yield from commercial compounds is described. The key step involves a highly enantioselective α-amination reaction of an acyclic β-ketoester with di-tert-butyl azodicarboxylate indu