1281979-66-5Relevant academic research and scientific papers
Pyrazoline derivatives as tubulin polymerization inhibitors with one hit for Vascular Endothelial Growth Factor Receptor 2 inhibition
Yang, Bing,Zhou, Jiahua,Wang, Fa,Hu, Xiao-Wei,Shi, Yujun
, (2021/07/13)
In this work, to check the effect of the transposition of the rings in typical patterns, a series of pyrazoline derivatives 3a-3t bearing the characteristic 3,4,5-trimethoxy phenyl and thiophene moieties were synthesized and evaluated as tubulin polymeriz
Synthesis and structural studies of isomeric Δ2- pyrazolines
Ingle,Doshi,Raut
experimental part, p. 1517 - 1520 (2011/10/13)
1-(2′-Thienyl)-3-(4″-dimethylamino phenyl)-2-propen-1-one(la-e) react with hydrazine hydrochloride in DMF medium to give isomeric 1-H pyrazolines (lla-e), react with phenyl hydrazine hydrochloride in DMF medium to give isomeric 1 -phenyl pyrazolines (Illa
