128228-96-6Relevant articles and documents
Reductive deacetylation of 3,3,3-trifluoro-1-(2-thenoyl)acetone
Russavskaya,Grabel'nyh,Deryagina,Korchevin
, p. 868 - 871 (2006)
The reaction of 3,3,3-trifluoro-1-(2-thenoyl)acetone with sulfur-hydrazine hydrate-alkali and hydrazine hydrate-alkali systems is effected by reductive fission of the trifluoroacetyl group and leads to the formation of nitrogen-containing derivatives of 2-acetylthiophene. Sodium polysulfide assists the reductive fission of 3,3,3-trifluoro-1-(2-thenoyl)acetone.
Synthesis of 1,1,1-trihalo-4-methoxy-4-[2-heteroaryl]-3-buten-2-ones, the corresponding butan-1,3-dione and azole derivatives
Flores, Alex F.C,Brondani, Sergio,Zanatta, Nilo,Rosa, Adriano,Martins, Marcos A.P
, p. 8701 - 8705 (2007/10/03)
The synthesis of 1,1,1-trihalo-4-methoxy-4-[2-thienyl]-3-buten-2-ones, 1,1,1-trihalo-4-methoxy-4-[2-furyl]-3-buten-2-ones and the respective trihalomethyl 1,3-butanone derivatives by trihaloacylation of dimethoxy acetals derived from 2-acetylthiophene and 2-acetylfuran are reported. This is a convenient method to obtain fluorinated and chlorinated 1,3-dielectrophiles from 2-acetylthiophene and 2-acetylfuran. The fluorinated 1,3-dielectrophiles were used to synthesize five new 2-thienyl- and 2-furylazoles. The structure of all products were assigned by 1HH- and 13C NMR and mass spectrometry.