128242-92-2Relevant academic research and scientific papers
Convenient preparation of substituted 5-aminooxazoles via a microwave-assisted Cornforth rearrangement
Nolt, M. Brad,Smiley, Mark A.,Varga, Sandor L.,McClain, Ray T.,Wolkenberg, Scott E.,Lindsley, Craig W.
, p. 4698 - 4704 (2007/10/03)
The preparation of oxazole-4-carboxamides and their subsequent thermal rearrangement to 5-aminooxazole-4-carboxylates is optimized in a high-speed microwave-assisted procedure. The reaction sequence is effective with a variety of substituted oxazoles, and produces products in good yield and high purity.
