128256-21-3

Upstream product

• 66275-61-4 N-Chloro-N'-(4-methylphenyl)benzamidine 
• 71316-14-8 N'-(4-methylphenyl)-N-(triphenylphosphoranylidene)-benzenecarboximidamide 
• 104-55-2 3-phenyl-propenal 
• 104-53-0 3-phenyl-propionaldehyde 

Relevant academic research and scientific papers

A convenient synthesis of Quinazoline ring by tandem aza-Wittig reaction/electrocyclic ring closure

3,4-D-Dihydroquinazolines and Quinazolines were prepared starting from N'-aryl-N-(triphenylphosphoranilidene)-carboximidamides and aliphatic or aromatic aldehydes. The mechanism of the reaction is discussed.

Quinazolines by electrocyclic ring closure of 1,3-diaza-1,3-dienes

N-imidoyliminotripheny]phosphorane reacts with aliphatic and aromatic aldehydes to give via an 1,3-diaza-1,3-diene intermediate 3,4-dihydro quinazolines and quinazolines. The ratio between the reaction products depends from the aldehyde employed.