128293-66-3

Upstream product

• 128293-65-2 benzyl 4-((tert-butoxycarbonyl)amino)-1-methyl-1H-imidazole-2-carboxylate 
• 1006381-83-4 C₁₂H₁₁N₃O₄ 

Downstream Products

• 128293-67-4 benzyl 4-formylamino-1-methylimidazole-2-carboxylate 

Relevant academic research and scientific papers

N-formamido-containing mono- and diheterocyclic pyrrole-and imidazole-2-carboxylic acids as building blocks for polyamide synthesis

Four N-formamido-containing mono-and diheterocyclic pyrrole- and imidazole-2-containing acids 1-4 were synthesized as intermediates for the preparation of polyamide molecules. The N-formamido-moiety forces the compounds to bind strongly as a stacked dimer, and in a staggered fashion, at specific sequences in the minor-groove of DNA. The acid moiety at the C-terminus of compounds enables these molecules to be coupled to amine-containing intermediates to form the amide linkages of the target polyamide. This convergent approach increases the synthetic diversity in polyamide chemistry by enabling one acid to be used with a variety of different C-terminus- functionalized intermediates. Copyright Taylor & Francis Group, LLC.

The Preparation and Properties of Partially Protected 4-Amino-1-methylimidazole-2-carboxylic Acids to be Used as Intermediates in the Synthesis of Analogues of Distamycin A

Partially protected 4-amino-1-methylimidazole-2-carboxylic acid derivatives have been prepared by a convenient route from the corresponding nitro analogue.Such derivatives, blocked on the amino function with tert-butyloxycarbonyl (4) or formyl groups (8)