1283083-10-2Relevant academic research and scientific papers
Organocatalytic addition on l,2-bis(sulfone)vinylenes leading to an unprecedented rearrangement
Quintard, Adrien,Alexakis, Alexandre
supporting information; experimental part, p. 11109 - 11113 (2010/04/29)
A study was conducted to demonstrate the use of 1,2-bis(sulfone)vinylenes in enamine catalysis. It was revealed that these sulfones led to a new rearrangement arising from a sulfone shift to the adjacent carbon atom. Investigations also revealed that the use of cheaper (Z)-1,2-bis(sulfone) vinylene lead to full conversion after a short reaction time in dioxane, using H2O as co-catalyst to accelerate the reaction. A careful NMR investigation indicated that the new product was gem-disulfone, which was supported by authentic sample.
