22751-68-4

Basic information

• Product Name: 1,2-Ethanediamine, N,N'-dimethyl-1,2-diphenyl-
• Synonyms: 1,2-Ethanediamine,N,N'-dimethyl-1,2-diphenyl
• CAS NO: 22751-68-4
• Molecular Formula: C16H20N2
• Molecular Weight: 240.348
• Mol File: 22751-68-4.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediamine, N,N'-dimethyl-1,2-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediamine, N,N'-dimethyl-1,2-diphenyl-(22751-68-4)
• EPA Substance Registry System: 1,2-Ethanediamine, N,N'-dimethyl-1,2-diphenyl-(22751-68-4)

Safety Data

• Hazardous Substances Data: 22751-68-4(Hazardous Substances Data)

Upstream product

• 622-29-7 N-Benzylidenemethylamine 
• 25521-74-8 N-benzylidenemethylamine 
• 100-52-7 benzaldehyde 
• 69019-77-8 N,N'-Dimethyl-1,2-diphenyl-N,N'-bis-trimethylsilanyl-ethane-1,2-diamine 
• 220665-71-4 N-((1S,2S)-2-Formylamino-1,2-diphenyl-ethyl)-formamide 
• 22751-68-4 (+/-)-N,N'-dimethyl-1,2-diphenyl-1,2-ethylenediamine 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 541-41-3 chloroformic acid ethyl ester 
• 60509-62-8 (R,S)-N,N'-dimethyl-1,2-diphenylethylenediamine 
• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 3969-04-8 Diethyl N,N'-(1,2-diphenylethylene)biscarbamate 
• 234753-20-9 diethyl ((1S,2S)-1,2-diphenylethane-1,2-diyl)dicarbamate 
• 6130-87-6 Tetramethyltetrazon 
• 100-51-6 benzyl alcohol 

Downstream Products

• 133643-21-7 (4S,5S)-2--1,3-dimethyl-4,5-diphenylimidazolidine 
• 128946-66-7 (E)-(S)-1-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oct-1-en-3-ol 
• 128860-91-3 (E)-(R)-1-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oct-1-en-3-ol 
• 119092-10-3 3-[3-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oxiranyl]-propionic acid methyl ester 
• 704890-52-8 2-chloro-1,3-dimethyl-4,5-diphenyl-1,3,2-diazaphospholidine 
• 64994-19-0 1,3-dimethyl-r-2,c-4,t-5-triphenylimidazolidine 
• 131035-33-1 2-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-benzaldehyde 
• 203062-94-6 (4S,5S)-2-Chloro-1,3-dimethyl-4,5-diphenyl-[1,3,2]diazaphospholidine 2-oxide 
• 234753-26-5 (S,S)-1,2-bis(N-methyl-α-chloroacetamido)-1,2-diphenylethane 
• 438207-07-9 (3S,4S)-2,5-dimethyl-1-(2-trimethylsiloxyphenyl)-2,5-diaza-4-phospholidine 

Relevant articles and documents

Development of Chiral Organosuperbase Catalysts Consisting of Two Different Organobase Functionalities

In the field of chiral Br?nsted base catalysis, a new generation of chiral catalysts has been highly anticipated to overcome the intrinsic limitation of pronucleophiles that are applicable to the enantioselective reactions. Herein, we reveal conceptually new chiral Br?nsted base catalysts consisting of two different organobase functionalities, one of which functions as an organosuperbase and the other as the substrate recognition site. Their prominent activity, which stems from the distinctive cooperative function by the two organobases in a single catalyst molecule, was demonstrated in the unprecedented enantioselective direct Mannich-type reaction of α-phenylthioacetate as a less acidic pronucleophile. The present achievement would provide a new guiding principle for the design and development of chiral Br?nsted base catalysts and significantly broaden the utility of Br?nsted base catalysis in asymmetric organic synthesis.

Dynamic Kinetic Resolution of Heterobiaryl Ketones by Zinc-Catalyzed Asymmetric Hydrosilylation

A diastereo- and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile heterobiaryl ketones is described. The DKR proceeds by zinc-catalyzed hydrosilylation of the carbonyl group, thus leading to secondary alcohols bearing axial and central chirality. The strategy relies on the labilization of the stereogenic axis that takes place thanks to a Lewis acid–base interaction between a nitrogen atom in the heterocycle and the ketone carbonyl group. The synthetic utility of the methodology is demonstrated through stereospecific transformations into either N,N-ligands or appealing axially chiral, bifunctional thiourea organocatalysts.

Indium trichloride: A versatile catalyst for the synthesis of fully saturated imidazoles

Ketimines are readily reduced to corresponding vicinal diamines using InCl3 and zinc followed by simple cyclization to fully saturated imidazoles with various aldehydes. InCl3 has been found to play an efficient catalytic role for th