128322-52-1Relevant academic research and scientific papers
Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst
Utsumi, Tatsuki,Noda, Kenta,Kawauchi, Daichi,Ueda, Hirofumi,Tokuyama, Hidetoshi
supporting information, p. 3583 - 3588 (2020/08/05)
Herein, a Grubbs-catalyzed route for the synthesis of nitriles via the aerobic oxidation of primary amines is reported. This reaction accommodates a variety of substrates, including simple primary amines, sterically hindered β,β-disubstituted amines, allylamine, benzylamines, and α-amino esters. Reaction compatibility with various functionalities is also noted, particularly with alkenes, alkynes, halogens, esters, silyl ethers, and free hydroxyl groups. The nitriles were also synthesized via the oxidation of imines generated from aldehydes and NH4OAc in situ. (Figure presented.).
SELECTIVE HYDROGENATION OF ORGANIC AZIDES TO AMINES BY INTERLAMELLAR MONTMORILLONITEDIPHENYLPHOSPHINE PALLADIUM(II) CATALYST
Sharma, G. V. M.,Chandrasekhar, S.
, p. 3289 - 3294 (2007/10/02)
Organic azides are selectively and catalytically hydrogenated to amines by a heterogenized homogeneous catalyst for the first time.
