128333-12-0

Basic information

• Product Name: Cyclohexyl 1,2-dihydro-4-methoxybenzocyclobuten-1-yl ketone
• CAS NO: 128333-12-0
• Molecular Weight: 244.334
• Mol File: 128333-12-0.mol

Chemical Properties

• CAS DataBase Reference: Cyclohexyl 1,2-dihydro-4-methoxybenzocyclobuten-1-yl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexyl 1,2-dihydro-4-methoxybenzocyclobuten-1-yl ketone(128333-12-0)
• EPA Substance Registry System: Cyclohexyl 1,2-dihydro-4-methoxybenzocyclobuten-1-yl ketone(128333-12-0)

Safety Data

• Hazardous Substances Data: 128333-12-0(Hazardous Substances Data)

Upstream product

• 56437-05-9 1-cyano-4-methoxybenzocyclobutane 
• 4630-82-4 methyl cyclohexylcarboxylate 
• 60100-19-8 4-methoxybenzocyclobutene-1-carboxylic acid 

Downstream Products

• 128333-19-7 1-(1-Cyclohexylvinyl)-1,2-dihydro-4-methoxybenzocyclobutene 
• 128333-26-6 2-Cyclohexyl-3,4-dihydro-6-methoxynaphthalene 
• 128333-30-2 2-Cyclohexyl-6-methoxynaphthalene 
• 59115-43-4 2-methoxy-6-phenylnaphthalene 

Relevant articles and documents

Synthesis of 2,6-Disubstituted Dihydronaphthalenes and Naphthalenes by Electrocyclic Reaction of o-Quinodimethane. A Synthesis of (+/-)-Naproxen

A survey of the electrocyclic reactions of o-quinodimethanes generated in situ by the thermolysis of dihydrobenzocyclobutenes with a variety of olefinic substituents at C-1 is reported.These reactions provide convenient access to the 2,6-disubstituted dihydronaphthalenes (11) and the naphthalenes (12).Thermolysis of the benzocyclobutenes (10) at 180 deg C in the presence of manganese dioxide affords in good yields the 2,6-di- and 2,3,6-tri-substituted naphthalenes (12) and (16).The naphthalenes (12b,f,h) thus obtained were easily converted into (+/-)-naproxen (5).