1283593-50-9Relevant academic research and scientific papers
New procedure for the preparation of (Z)-2-(5-amino-1,2,4-thiadiazole-3-yl) -2-trityloxyiminoacetic acid
Zhong, Weihui,Zhang, Wendong,Chen, Yanhui,Liu, Yanbin,Yao, Yi
, p. 698 - 703 (2011/12/01)
A novel and efficient procedure has been developed for the preparation of the C-7 side chain of ceftobiprole, (Z)-2-(5-amino-1,2,4-thiadiazole-3-yl)-2- trityloxyiminoacetic acid (2) from malononitrile (9) in a total yield of 19%. The key intermediate N-(3
