1283713-72-3

Upstream product

• 197227-70-6 (2E)-4-[(4-methoxybenzyl)oxy]-2-methylbut-2-enal 
• 200440-90-0 ((3R)-3-{[dihydroxy(methyl)-λ⁴-sulfanyl]oxy}but-1-yn-1-yl)(trimethyl)silane 
• 1283713-43-8 (3S,4S,E)-7-(4-methoxybenzyloxy)-3,5-dimethyl-1-(trimethylsilyl)hept-5-en-1-yn-4-ol 
• 69739-34-0 t-butyldimethylsiyl triflate 

Downstream Products

• 1283713-73-4 C₂₃H₃₅IO₃Si 
• 1283713-44-9 1-(((2E,4S,5S,6Z)-4-tert-butyldimethylsilyloxy-7-iodo-3,5-dimethylhepta-2,6-dienyloxy)methyl)-4-methoxybenzene 

Relevant academic research and scientific papers

Synthetic studies towards leiodermatolide: Rapid stereoselective syntheses of key fragments

The synthesis of three key fragments of the novel 16-membered macrolide leiodermatolide is described. The stereotetrad-containing building block was prepared via a Marshall-Tamaru reaction on an aldehyde obtained by organocatalysis. For a second building block, a Marshall-Tamaru reaction was used as well. The side-chain fragment containing a hydroxy δ-lactone could be obtained by intramolecular Reformatsky reaction. Georg Thieme Verlag Stuttgart.