1283718-72-8 Usage
Uses
Used in Pharmaceutical Industry:
Tert-butyl 3-amino-4,4-difluoropiperidine-1-carboxylate is utilized as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, enhancing the potency and selectivity of the resulting drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, tert-butyl 3-amino-4,4-difluoropiperidine-1-carboxylate serves as a valuable component in the design and synthesis of novel bioactive molecules. Its unique structural features, including the presence of fluorine atoms, contribute to the modulation of physicochemical properties and biological activities of the compounds under investigation.
Used in Organic Synthesis:
Tert-butyl 3-amino-4,4-difluoropiperidine-1-carboxylate is employed as a versatile building block in organic synthesis, allowing for the creation of a diverse range of organic compounds with potential applications in various industries, including materials science, agrochemicals, and specialty chemicals. Its reactivity and functional group compatibility make it a preferred choice for synthetic chemists.
Check Digit Verification of cas no
The CAS Registry Mumber 1283718-72-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,3,7,1 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1283718-72:
(9*1)+(8*2)+(7*8)+(6*3)+(5*7)+(4*1)+(3*8)+(2*7)+(1*2)=178
178 % 10 = 8
So 1283718-72-8 is a valid CAS Registry Number.
1283718-72-8Relevant academic research and scientific papers
DIACYLGLYCEROL ACYL TRANSFERASE 2 INHIBITOR
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Paragraph 0272; 0369, (2021/04/10)
Described herein are compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are defined herein, their use as diacylglycerol acyltransferase 2 (DGAT2) inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, NASH.
HETEROCYCLIC COMPOUND
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, (2017/08/01)
The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.
