128372-49-6Relevant academic research and scientific papers
Organocatalytic asymmetric 1,4-addition of organoboronic acids to γ-hydroxy α,β-unsaturated aldehyde: facile synthesis of chiral β-substituted γ-lactones
Kim, Sung-Gon
supporting information; body text, p. 6148 - 6151 (2009/04/05)
Catalytic asymmetric 1,4-addition of arylvinyl- and arylboronic acids to a γ-hydroxy α,β-unsaturated aldehyde, which affords β-substituted γ-lactols, has been established using a diarylprolinol silyl ether as an organocatalyst. The β-substituted γ-lactols have been obtained in good yields and with up to 91% ee, which lead to chiral β-substituted γ-lactones followed by oxidation.
A FACILE SYNTHESIS OF 4-ARYLBUTYROLACTONES VIA THE PALLADIUM-CATALYZED ARYLATION OF 1,3-DIOXEP-5-ENE
Sakamoto, Takao,Kondo, Yoshinori,Yamanaka, Hiroshi
, p. 2437 - 2440 (2007/10/02)
1,3-Dioxep-5-ene was arylated by using Heck reaction, and the arylated 1,3-dioxep-5-ene derivatives were easily converted into 4-arylbutyrolactones, intermediates for the synthesis of natural products and biological active compounds.
β-vinyl-γ-butyrolactones via the palladium-catalysed reaction of vinyl triflates with Z-2-buten-1,4-diol
Arcadi,Bernocchi,Cacchi,Marinelli
, p. 1525 - 1540 (2007/10/02)
The palladium-catalysed reaction of vinyl triflates with Z-2-buten-1,4-diol affords β-vinyl-γ-butyrolactols (4-vinyl-2-hydroxy-tetrahydrofurans) which are converted into the corresponding β-vinyl-γ-butyrolactones by a smooth oxidation with Ag2C
