128372-49-6Relevant articles and documents
Organocatalytic asymmetric 1,4-addition of organoboronic acids to γ-hydroxy α,β-unsaturated aldehyde: facile synthesis of chiral β-substituted γ-lactones
Kim, Sung-Gon
supporting information; body text, p. 6148 - 6151 (2009/04/05)
Catalytic asymmetric 1,4-addition of arylvinyl- and arylboronic acids to a γ-hydroxy α,β-unsaturated aldehyde, which affords β-substituted γ-lactols, has been established using a diarylprolinol silyl ether as an organocatalyst. The β-substituted γ-lactols have been obtained in good yields and with up to 91% ee, which lead to chiral β-substituted γ-lactones followed by oxidation.
β-vinyl-γ-butyrolactones via the palladium-catalysed reaction of vinyl triflates with Z-2-buten-1,4-diol
Arcadi,Bernocchi,Cacchi,Marinelli
, p. 1525 - 1540 (2007/10/02)
The palladium-catalysed reaction of vinyl triflates with Z-2-buten-1,4-diol affords β-vinyl-γ-butyrolactols (4-vinyl-2-hydroxy-tetrahydrofurans) which are converted into the corresponding β-vinyl-γ-butyrolactones by a smooth oxidation with Ag2C
