1283722-16-6Relevant academic research and scientific papers
Direct Catalytic Asymmetric Aldol Reaction of Thioamide with an α-Vinyl Appendage
Cui, Jin,Ohtsuki, Akimichi,Watanabe, Takumi,Kumagai, Naoya,Shibasaki, Masakatsu
, p. 2598 - 2601 (2018)
The direct catalytic asymmetric aldol reaction is an emerging catalytic methodology that provides atom-economical access to functionalized chiral building blocks. Thioamides are useful aldol donors due to their high-fidelity chemoselective enolization and
Direct catalytic enantio- and diastereoselective aldol reaction of thioamides
Iwata, Mitsutaka,Yazaki, Ryo,Chen, I-Hon,Sureshkumar, Devarajulu,Kumagai, Naoya,Shibasaki, Masakatsu
, p. 5554 - 5560 (2011/05/14)
A direct catalytic asymmetric aldol reaction of thioamides using a soft Lewis acid/hard Bronsted base cooperative catalyst comprising (R,R)-Ph-BPE/[Cu(CH3CN)4]PF6/LiOAr is described. Exclusive enolate generation from thioa
