1283746-90-6Relevant academic research and scientific papers
Palladium-catalyzed oxidative insertion of carbon monoxide to N -sulfonyl-2-aminobiaryls through C-H bond activation: Access to bioactive phenanthridinone derivatives in one pot
Rajeshkumar, Venkatachalam,Lee, Tai-Hua,Chuang, Shih-Ching
, p. 1468 - 1471 (2013/06/26)
Palladium-catalyzed oxidative carbonylation of N-sulfonyl-2-aminobiaryls through C-H bond activation and C-C, C-N bond formation under TFA-free and milder conditions has been developed. The reaction tolerates a variety of substrates and provides biologically important phenanthridinone derivatives in yields up to 94%.
Palladium-catalyzed and hybrid acids-assisted synthesis of [60]fulleroazepines in one pot under mild conditions: Annulation of N-sulfonyl-2-aminobiaryls with [60]fullerene through sequential C-H bond activation, C-C and C-N bond formation
Rajeshkumar, Venkatachalam,Chan, Fu-Wei,Chuang, Shih-Ching
, p. 2473 - 2483,11 (2020/08/31)
An extraordinarily efficient hybrid acids-assisted, palladium-catalyzed and chelating-group-assisted C-H bond activation of N-sulfonyl-2-aminobiaryls and their annulations with [60]fullerene via sequential C-C and C-N bond formation at room temperature to
Intramolecular oxidative C-N bond formation for the synthesis of carbazoles: Comparison of reactivity between the copper-catalyzed and metal-free conditions
Cho, Seung Hwan,Yoon, Jungho,Chang, Sukbok
, p. 5996 - 6005 (2011/06/11)
New synthetic procedures for intramolecular oxidative C-N bond formation have been developed for the preparation of carbazoles starting from N-substituted amidobiphenyls under either Cu-catalyzed or metal-free conditions using hypervalent iodine(III) as an oxidant. Whereas iodobenzene diacetate or bis(trifluoroacetoxy)iodobenzene alone undergoes the reaction to provide carbazole products in moderate to low yields, combined use of copper(II) triflate and the iodine(III) species significantly improves the reaction efficiency, giving a more diverse range of products in good to excellent yields. On the basis of mechanistic studies including kinetic profile, isotope effects, and radical inhibition experiments, the copper species is proposed to catalytically activate the hypervalent iodine(III) oxidants. The synthetic utility of the present approach was nicely demonstrated in a direct synthesis of indolo[3,2-b]carbazole utilizing a double C-N bond formation.
