128404-37-5

Basic information

• Product Name: (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL
• Synonyms: (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL;(S)-2,2,2-Trifluoro-1-phenylethylamine hydrochloride;(1S)-2,2,2-trifluoro-1-phenylethan-1-aMine hydrochloride;(S)-2,2,2-Trifluoro-1-phenylethanaMine hydrochloride;BenzeneMethanaMine, a-(trifluoroMethyl)-, hydrochloride, (aS)-;(1S)-2,2,2-trifluoro-1-phenylethanamine,hydrochloride;(S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HYDROCHLRIDE
• CAS NO: 128404-37-5
• Molecular Formula: C8H9ClF3N
• Molecular Weight: 211.61
• Product Categories: pharmacetical
• Mol File: 128404-37-5.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 237.7 °C at 760 mmHg
• Flash Point: 97.6 °C
• Appearance: /
• Vapor Pressure: 0.0356mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(128404-37-5)
• EPA Substance Registry System: (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(128404-37-5)

Safety Data

• Hazardous Substances Data: 128404-37-5(Hazardous Substances Data)

Usage

General Description

(S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL is a chemical compound with the molecular formula C8H10F3N·HCl. It is a salt form of (S)-2,2,2-trifluoro-1-phenylethylamine, which is a chiral amine. (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL is often used as an intermediate in the pharmaceutical and agrochemical industries for the synthesis of various biologically active molecules. It is also used in the preparation of chiral catalysts and ligands for asymmetric synthesis. The HCl salt form of this compound is often preferred due to its better solubility and stability in various solvents. Additionally, it is important to handle (S)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL with proper care and safety protocols, as it is a corrosive and potentially hazardous compound.

InChI:InChI=1/C8H8F3N.ClH/c9-8(10,11)7(12)6-4-2-1-3-5-6;/h1-5,7H,12H2;1H/t7-;/m0./s1

Upstream product

• 1223578-73-1 (S(S),R)-N-(2,2,2-trifluoro-1-phenylethyl)-2-propanesulfinamide 
• 1258542-26-5 (Rs,R)-N-(2,2,2-trifluoro-1-phenylethyl)-tert-butanesulfinamide 
• 1334287-93-2 (S)-4-methoxy-N-(2,2,2-trifluoro-1-phenylethyl)aniline 
• 1190864-56-2 3-(((S)-2,2,2-trifluoro-1-phenylethyl)amino)-3-methylbutanamide 
• 885315-17-3 (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide 
• 62197-91-5 N-(1-phenylethyl)-2,2,2-trifluoro-1-phenylethan-1-imine 
• 119561-19-2 N-(1-phenyl-2,2,2-trifluoroisopropylidene)benzylamine 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 119561-20-5 N-benzylidene(1-phenyl-2,2,2-trifluoroethyl)amine 
• 128404-36-4 [1-Phenyl-eth-(E)-ylidene]-(2,2,2-trifluoro-1-phenyl-ethyl)-amine 

Relevant articles and documents

Thermal 1,3-proton shift reaction and its application for operationally convenient and improved synthesis of α-(trifluoromethyl)benzylamine

This paper describes a synthesis of α-(trifluoromethyl)benzylamine via a novel base-free biomimetic reductive amination of α,α,α-trifluoroacetophenone with benzylamine. When the corresponding imine, derived from α,α,α-trifluoroacetophenone and benzylamine

METHOD FOR PRODUCING OPTICALLY ACTIVE TRIFLUOROMETHYL GROUP-CONTAINING AMINO ACID DERIVATIVE

PROBLEM TO BE SOLVED: To provide methods for producing optically active trifluoromethyl group-containing sulfinamide derivatives and optically active amino acids/hydrochlorides, using trifluoromethane as a generator of trifluoromethyl anions. SOLUTION: Th

Diastereoselective addition of organomagnesium and organolithium reagents to chiral trifluoromethyl N-tert-butanesulfinyl hemiaminals

The asymmetric synthesis of trifluoromethylated tertiary and secondary carbinamines (α,α-dibranched and α-branched amines) was achieved by reaction of alkyl, aryl and allyl organomagnesium or organolithium reagents to trifluoromethyl N-tert-butanesulfinyl