128405-31-2Relevant academic research and scientific papers
Reactions with 2(1H)-quinolinone and coumarine derivatives: New routes to polysubstituted 2(1H)-quinolinone and coumarine derivatives
El-Taweel,Sowellim,Elagamey
, p. 905 - 910 (2007/10/02)
Whereas 2H-pyrano[3,2-c[quinoline-2,5(6H)-dione (2a) or 3-acetyl-1-methyl-2(1H)-quinolinone (3a) reacted with the benzylidenenitriles 1a-f or a mixture of either malononitrile or ethyl cyanoacetate and aromatic aldehydes in ethanol/piperidine to give 4H-pyran derivatives 8, the reaction of 2b,c or 3b,c with the same reagents afforded 4,6-dihydro-5H-pyrano[3,2-c]quinolin-5-ones 11. Compounds 11 were also prepared from 1a-f and 3d,e,f. Reaction of pyrano[3,2-c]coumarin 2d with 1a yielded 6H,11H-[2]benzopyrano[4,3-c]-[1]benzopyran-6,11-dione (15). Treatment of 17 with aqueous potassium cyanide or hydroxylamine afforded the 2(1H)-quinolinone derivatives 19 and 20 respectively.
NITRILES IN HETEROCYCLIC SYNTHESIS: A NOVEL ROUTE FOR THE SYNTHESIS OF NAPHTHODIPYRANS, PYRIDINES. 2H- AND 4H-PYRANS
Elagamey, Abdel Ghani A.,El-Taweel, Fathy M. A.,Sowellim, Salah Z. A.,Sofan, Mamdouh A.,Elnagdi, Mohamed H.
, p. 524 - 534 (2007/10/02)
Naphthodipyrans, naphthodipyrans and naphthodipyrans were synthesized by the reaction of cinnamonitriles with 2,3-, 1,5-, 1,6-naphthalenediols, respectively.Polysubstituted pyridines, 2H-pyrans and 4H-pyrans were
