1284221-70-0Relevant articles and documents
Concise synthesis of 1,3-di-O-substituted tetrahydropyran derivatives as conformationally stable pyranose mimetics
Mydock, Laurel K.,Spilling, Christopher D.,Demchenko, Alexei V.
, p. 301 - 306 (2011)
A practical synthetic route to 1,3-di-O-substituted tetrahydropyrans has been developed. An important feature of these obtained glycomimetics is the bulky t-butyl functionality at the C-4 position, which imposes a chair conformation as the lowest energy conformer, making these compounds ideal pyranose mimetics.