443284-35-3Relevant academic research and scientific papers
Concise synthesis of 1,3-di-O-substituted tetrahydropyran derivatives as conformationally stable pyranose mimetics
Mydock, Laurel K.,Spilling, Christopher D.,Demchenko, Alexei V.
, p. 301 - 306 (2012/03/09)
A practical synthetic route to 1,3-di-O-substituted tetrahydropyrans has been developed. An important feature of these obtained glycomimetics is the bulky t-butyl functionality at the C-4 position, which imposes a chair conformation as the lowest energy conformer, making these compounds ideal pyranose mimetics.
Novel chiral lipoxygenase substrates: Design and synthesis. Part 2
Yadav,Nanda
, p. 3223 - 3234 (2007/10/03)
A series of novel lipoxygenase substrates carrying a spacing modifier with a non-ionic hydroxyl terminus have been synthesized in an enantioselective fashion. One of the methylene hydrogens (flanked by the cis,cis-pentadienyl moiety) is replaced by alkyl,
