1284423-17-1

Upstream product

• 3959-07-7 4-Bromobenzylamine 
• 1939-99-7 benzenesulfonyl chloride 

Downstream Products

• 1445719-73-2 N-isobutyl-N-(4'-methanesulfonylbiphenyl-4-ylmethyl)-C-phenylmethanesulfonamide 
• 1445720-19-3 N-isopropyl-N-[5-(4-methanesulfonylphenyl)thiophen-2-ylmethyl]-C-phenylmethanesulfonamide 
• 1445720-38-6 N-(4-bromobenzyl)-N-isobutyl-1-phenylmethanesulfonamide 
• 1445720-45-5 N-((5-(4-(methylsulfonyl)phenyl)thiophen-2-yl)methyl)-1-phenylmethanesulfonamide 
• 1445902-97-5 N-(4-(4-acetylpiperazin-1-yl)benzyl)-1-phenylmethanesulfonamide 
• 1445901-27-8 N-[4-(4-cyclopropanecarbonyl-piperazin-1-yl)-benzyl]-N-isobutyl-C-phenyl-methanesulfonamide 
• 1445901-40-5 N-[4-(4-acetylpiperazin-1-yl)benzyl]-1-phenyl-N-(2,2,2-trifluoroethyl)methanesulfonamide 

Relevant academic research and scientific papers

BENZYL SULFONAMIDE DERIVATIVES AS RORc MODULATORS

Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, A, B, C, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.

BENZYL SULFONAMIDE DERIVATIVES AS RORc MODULATORS

Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, n, A, X1, X2, X3, X4, R1, R2, R3a, R3b, R4a and R4b are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.