128453-98-5

Usage

Uses

Used in Pharmaceutical Industry:
(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID serves as a key building block in the organic synthesis of various pharmaceuticals. Its role is crucial for the development of new compounds with potential therapeutic applications, given its ability to contribute to the formation of biologically active molecules.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID is utilized for the preparation of agrochemicals. Its incorporation into the synthesis process aids in creating molecules that can be used in agricultural applications to improve crop protection and yield.
Used in Organic Synthesis:
(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID is employed as a reagent in organic synthesis for the production of complex organic molecules. Its unique properties facilitate the creation of new compounds that may possess valuable chemical and biological properties.
Used in Chemical Research:
As a reagent in chemical research, (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID is instrumental in studying and understanding various chemical reactions and mechanisms. Its presence in experimental setups can provide insights into the behavior of molecules and the potential for new discoveries in the field of chemistry.

InChI:InChI=1/C10H17NO4S/c1-10(2,3)15-9(14)11-4-5-16-6-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 96612-95-2 thiomorpholine-3-carboxylic acid hydrochloride 
• 123-91-1 1,4-dioxane 
• 20960-92-3 perhydro-1,4-thiazine-3-carboxylic acid 
• 58729-31-0 ethyl thiomorpholine-3-carboxylate 

Downstream Products

• 1352343-91-9 C₂₅H₂₅F₅N₄O₅S 
• 1400284-01-6 C₂₀H₂₅N₃O₄S₂ 
• 1400283-68-2 C₂₂H₂₃N₃O₄S₃ 

Relevant academic research and scientific papers

INHIBITORS OF HEPATITIS C VIRUS

The present application includes novel inhibitors of HCV, compositions containing such compounds, therapeutic methods that include the administration of such compounds.

Discovery and synthesis of HIV integrase inhibitors: Development of potent and orally bioavailable N-methyl pyrimidones

The human immunodeficiency virus type-1 (HIV-1) encodes three enzymes essential for viral replication: a reverse transcriptase, a protease, and an integrase. The latter is responsible for the integration of the viral genome into the human genome and, therefore, represents an attractive target for chemotherapeutic intervention against AIDS. A drug based on this mechanism has not yet been approved. Benzyl-dihydroxypyrimidine-carboxamides were discovered in our laboratories as a novel and metabolically stable class of agents that exhibits potent inhibition of the HIV integrase strand transfer step. Further efforts led to very potent compounds based on the structurally related N-Me pyrimidone scaffold. One of the more interesting compounds in this series is the 2-N-Me-morpholino derivative 27a, which shows a CIC95 of 65 nM in the cell in the presence of serum. The compound has favorable pharmacokinetic properties in three preclinical species and shows no liabilities in several counterscreening assays.

Compounds, compositions, and methods for stimulating neuronal growth and elongation

The present invention concerns methods, pharmaceutical compounds, and compositions for stimulating neuroite outgrowth in nerve cells leading to nerve regeneration. These methods, compounds and compositions inhibit rotamase enzyme activity associated with binding proteins.

Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them

Analgesic compounds are of the general formula (I): STR1 in which, R1 and R2 each represents hydrogen or C1 -C6 alkyl, or R1 and R2 together with the nitrogen atom to which they are attache