128519-80-2Relevant academic research and scientific papers
Preparation and chemistry of some 1,5-diphenyl-1λ4,2,4- thiadiazine 1-oxides
Jones, Stuart D.,Kennewell, Peter D.,Tulley, W. Roger,Westwood, Robert,Sammes, Peter G.
, p. 447 - 455 (2007/10/02)
General methods for the preparation of 3-substituted 5-aryl- 1λ4,2,4-thiadiazine 1-oxides are described. The chemical properties of these new heterocyclic systems have been explored, for example their susceptibility to electrophilic and nucleophilic attack. The 3-bromomethyl derivative can undergo a base-catalysed ring expansion to a seven-membered thiadiazepine; some initial studies at generating fused bicyclic systems from these heterocyclic precursors are also reported.
