128537-05-3

Upstream product

• 128537-04-2 Methyl 2-O-benzyl-4-chloro-3,4,6-trideoxy-α-D-xylo-hexopyranoside 
• 128537-00-8 methyl 2-O-benzyl-3,6-dideoxy-α-D-ribo-hexopyranoside 
• 50272-15-6 methyl 2-O-benzyl-3,6-dideoxy-α-D-ribo-hexopyranoside 
• 128536-99-2 Methyl 4-O-acetyl-2-O-benzyl-3,6-dideoxy-α-D-ribo-hexopyranoside 
• 65530-28-1 methyl 4,6-O-benzylidene-3-deoxy-α-D-glucopyranoside 
• 138665-01-7 Methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-α-D-ribo-hexopyranoside 
• 100-39-0 benzyl bromide 
• 65556-00-5 methyl 4,6-di-O-benzylidene-2,3-di-O-tosyl-α-D-glucopyranoside 
• 56783-67-6 2-O-benzyl-3,6-dideoxy-α-D-xylo-hexopyranoside 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Novel and convenient method for the syntheses of 2,6-dideoxypyranoses, 3,6-dideoxypyranoses, and azido (amino) analogs of 3,6-dideoxypyranoses

A novel method of regioselective deoxygenation of methyl 4,6-O-benzylidene-2,3-di-O-tosyl-α-D-glucopyranoside, and its application for the syntheses of 2,6-dideoxypyranoses, 3,6-dideoxypyranoses, and azido (amino) analogs of 3,6-dideoxypyranoses were reported.

Synthesis and biological activities of methyl oligobiosaminide and some deoxy isomers thereof.

Methyl oligobiosaminide (1) the core structure of oligostatin C, and five analogues, the 6-hydroxy-(2), 2-deoxy- (3), 2-deoxy-6-hydroxy- (4), 3-deoxy- (5), and 3-deoxy-6-hydroxy derivatives (6), were synthesized by coupling the protected pseudo-sugar epoxide 46 with suitable methyl 4-amino-4-deoxy-alpha-D-hexopyranoside derivatives. Compounds 3 and 6 showed notable inhibitory activity against alpha-D-glucosidase and alpha-D-mannosidase, respectively, whereas compound 1 had almost no activity.