1285464-68-7

Upstream product

• 62053-06-9 6-(2-hydroxyethyl)-5-methyl-1,2,4-triazolo<1,5-a>pyrimidin-7(4H)-one 
• 62053-05-8 7-chloro-6-(2-chloroethyl)-5-methyl-1,2,4-triazolo<1,5-a>pyrimidine 
• 22038-85-3 (R)-(-)-2,2,2-Trifluoro-1-phenylethylamine 
• 890040-25-2 trifluoromethanesulfonic acid 2,2,2-trifluoro-1-(S)-phenylethyl ester 
• 68210-20-8 7,8-dihydro-5-methyl-6H-pyrrolo<3,2-e><1,2,4>triazolo<1,5-a>pyrimidine 
• 340-06-7 S(+)-1-phenyl-2,2,2-trifluoroethanol 
• 655-25-4 2,2,2-trifluoroacetophenone oxime 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 

Relevant academic research and scientific papers

PYRROLO [3, 2 -E] [1,2,4] TRIAZOLO [1,5 -A] PYRIMIDINES DERIVATIVES AS INHIBITORS OF MICROGLIA ACTIVATION

The invention relates to novel compounds useful in the treatment and prophylaxis of disease. Compounds of the formula (I) wherein X is halogen, independently selected form chlorine and fluorine and n is 0, 1 or 2. and their pharmaceutically acceptable salts are useful in the treatment and prophylaxis of diseases caused by activation of microglia, particularly Alzheimer's disease.