1285658-68-5

Upstream product

• 261909-49-3 phenyl(isopropoxy-L-alaninyl) phosphorochloridate 
• 1158730-05-2 4'-azido-2'-deoxy-2'-methylarabinouridine 
• 151384-15-5 1-((2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 
• 1019639-21-4 C₁₀H₁₃IN₂O₄ 
• 1019639-22-5 C₁₀H₁₂N₂O₄ 
• 1158728-69-8 C₁₀H₁₂IN₅O₄ 
• 1019639-23-6 C₁₇H₁₆IN₅O₅ 

Relevant academic research and scientific papers

Azido nucleosides and nucleotide analogs

Disclosed herein are 4′-azido-substituted nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of 4′-azido-substituted nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a 4′-azido-substituted nucleoside, a nucleotide and/or an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.

PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDES

Compounds of formula I : including any possible stereoisomers thereof, wherein: R1 is hydrogen, -C(=O)R6 or -C(=O)CHR7-NH2; R2 is hydrogen; or C1-C6alkyl or phenyl, either of whi