1285670-38-3Relevant articles and documents
2-Trifluoroacetyl aminoindoles as useful intermediates for the preparation of 2-acylamino indoles
Mangette, John E.,Chen, Xuemei,Krishnamoorthy, Ravi,Samuel Vellekoop,Csakai, Adam J.,Camara, Fatoumata,Paquette, William D.,Wang, Hong-Jun,Takahashi, Hidenori,Fleck, Roman,Roth, Gregory P.
, p. 1292 - 1295 (2011/04/15)
A three-step method was developed to convert N-1 unprotected 3-substituted indoles to 3-substituted 2-acylaminoindoles. Established indole chlorination chemistry was employed to generate stable 2-trifluoroacetylamino indoles, which were subsequently deprotected and selectively acylated.
