128571-93-7

Basic information

• Product Name: 2-Azetidinecarboxaldehyde, 3-ethyl-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-rel-
• CAS NO: 128571-93-7
• Molecular Formula: C13H15NO3
• Molecular Weight: 233.267
• Mol File: 128571-93-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Azetidinecarboxaldehyde, 3-ethyl-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinecarboxaldehyde, 3-ethyl-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-rel-(128571-93-7)
• EPA Substance Registry System: 2-Azetidinecarboxaldehyde, 3-ethyl-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-rel-(128571-93-7)

Safety Data

• Hazardous Substances Data: 128571-93-7(Hazardous Substances Data)

Upstream product

• 24978-42-5 1,4-bis(4'-methoxyphenyl)-1,4-diazabuta-1,3-diene 
• 141-75-3 butyryl chloride 
• 124156-23-6 cis-3-Ethyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-20-3 (4-methoxyphenyl-benzylidene)-carbamic acid methyl ester 
• 24978-42-5 (E,E)-N¹,N²-bis(4-methoxyphenyl)ethane-1,2-diimine 
• 133504-94-6 (3S,4S)-3-Ethyl-1-(4-methoxy-phenyl)-4-{[(E)-4-methoxy-phenylimino]-methyl}-azetidin-2-one 
• 128474-72-6 cis-3-Ethyl-4-(hydroxymethyl)-1-(4-methoxyphenyl)azetidin-2-one 

Downstream Products

• 124223-53-6 cis-1-p-anisyl-3-ethyl-4-carboxy-2-azetidinone 
• 128474-72-6 cis-3-Ethyl-4-(hydroxymethyl)-1-(4-methoxyphenyl)azetidin-2-one 

Relevant articles and documents

Synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams

The synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams from imines derived from 4-formyl-β-lactams and α-amino esters via cascade imine → azomethine ylide → 1,3-dipolar cycloaddition reactions is described. These cascades are endo-specific, exhibit facial stereoselectivity and occur in good to excellent yields.

A novel, general, totally stereoselective one-pot synthesis of cis-3-substituted 4-formylazetidin-2-ones

A general, totally stereoselective one-pot synthesis of cis-3-substituted-4-formylazetidin-2-ones based upon the reaction of acid chlorides and 1,4-bis-(4-methoxyphenyl)-1,4-diazabuta-1,3-diene, as synthetic equivalent of the corresponding unknown α-formy

The acid chloride-iminoester condensation: A direct approach to PS-5 and PS-6 intermediates and related compounds

The dehydrochlorination of alkanoyl chlorides with triethylamine in the presence of α-iminoesters produced 3-alkyl-4-alkoxycarbonyl β-lactams in excellent yields and high stereoselectivity.