128626-83-5

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 45534-08-5 5-amino-3-methylthio-1,2,4-triazole 

Downstream Products

• 1542213-42-2 3-[(2-acetoxyethoxy)methyl]-2-methylthio-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidin-7-one 
• 1542213-55-7 3-[(2-hydroxyethoxy)methyl]-2-methylthio-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidin-7-one 

Relevant academic research and scientific papers

On Triazoles XIX: The Reaction of 5-Amino-1,2,4-triazoles with Functionalized Acetoacetic Esters

Different "functionalized" alkyl 3-oxo-butyrates (2) were reacted with 5-amino-3-Q-1H-1,2,4-triazoles (1) to yield 3 and 4 type 1,2,4-triazolopyrimidinones.In case of 2 (R1 = methyl, R2 = 1-ethoxycarbonylethyl, R3 = ethyl) beside the corresponding derivative 4 the unexpected 5,6-dihydro-6,8-dimethyl-7-ethoxycarbonyl-3-methylthio-1,2,4-triazolo-1,3-diazepin-5(9H)-one (7) was isolated, representing a novel ring system.