128640-74-4 Usage
Uses
Used in Pharmaceutical Industry:
4-CHLORO-6-(4-METHYLPHENYL)-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs, contributing to the advancement of medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CHLORO-6-(4-METHYLPHENYL)-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE is utilized as an intermediate for the production of agrochemicals. Its role in the synthesis of these compounds aids in the development of effective solutions for agricultural challenges.
Used as a Reagent in Chemical Research:
4-CHLORO-6-(4-METHYLPHENYL)-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE is also employed as a reagent in chemical reactions. It is used to produce various derivatives, which are essential for further research and development in both academic and industrial settings. This application highlights its importance in the ongoing pursuit of scientific discovery and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 128640-74-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,6,4 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 128640-74:
(8*1)+(7*2)+(6*8)+(5*6)+(4*4)+(3*0)+(2*7)+(1*4)=134
134 % 10 = 4
So 128640-74-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H10ClN3S/c1-8-3-5-9(6-4-8)11-10(7-15)12(14)17-13(16-11)18-2/h3-6H,1-2H3
128640-74-4Relevant academic research and scientific papers
Synthesis, antiplasmodial activity and mechanistic studies of pyrimidine-5-carbonitrile and quinoline hybrids
Kaur, Hardeep,Balzarini, Jan,De Kock, Carmen,Smith, Peter J.,Chibale, Kelly,Singh, Kamaljit
supporting information, p. 52 - 62 (2015/06/30)
Abstract A series of hybrids comprising of 5-cyanopyrimidine and quinoline moiety were synthesized and tested for in vitro antiplasmodial activity against NF54 and Dd2 strains of Plasmodium falciparum. Hybrid bearing m-nitrophenyl substituent at C-4 of py
Chemotherapeutic Agents. XVI. Synthesis of Pyrimidines and Fused Pyrimidines as Leishmanicides
Ram, Vishnu J.
, p. 957 - 963 (2007/10/02)
Various mono and bicyclic pyrimidine analogs (3-15) were prepared as leishmanicides from 6-aryl-4-chloro-2-methylthiopyrimidine-5-carbonitrile (2), obtained from the halogenation of 6-aryl-3,4-dihydro-2-methylthio-4-oxopyrimidine-5-carbonitrile (1).
