128654-33-1

Basic information

• Product Name: Benzene, 1-azido-4-ethyl-
• CAS NO: 128654-33-1
• Molecular Formula: C8H9N3
• Molecular Weight: 147.18
• Mol File: 128654-33-1.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzene, 1-azido-4-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-azido-4-ethyl-(128654-33-1)
• EPA Substance Registry System: Benzene, 1-azido-4-ethyl-(128654-33-1)

Safety Data

• Hazardous Substances Data: 128654-33-1(Hazardous Substances Data)

Upstream product

• 589-16-2 4-aminoethylbenzene 
• 25309-64-2 4-ethyl-1-iodobenzene 
• 63139-21-9 4-ethylphenylboronic acid 

Downstream Products

• 139192-89-5 2-amino-5-ethylphenyl methyl sulphide 
• 589-16-2 4-aminoethylbenzene 
• 1090350-96-1 C₁₈H₁₆N₂O 
• 1614257-11-2 2-[1-(4-ethylphenyl)-1H-[1,2,3]triazol-4-ylmethylsulfanyl]benzoxazole 
• 32804-22-1 4-ethyl-N-phenylbenzenamine 
• 1308787-56-5 N-(4-ethylphenyl)thiophen-3-amine 

Relevant articles and documents

Combinatorial synthesis of new fluorescent scaffolds using click chemistry

Azides and acetylenes are bio-orthogonal functional groups that can be readily coupled using copper(I)- or ruthenium(II)- catalyzed 1,3-dipolar cycloaddition reactions. Using non-fluorescent aromatic azides and aromatic acetylenes, covering a range of electron rich and poor building blocks, the Huisgen cycloaddition afford 1,4-disubstituted or 1,5-disubstituted 1,2,3-triazoles. Using a combinatorial approach by running reaction in parallel in polypropylene 96-well plates we discovered several new fluorescent 1,2,3-triazoles scaffolds. These compounds show diverse interactions with biomolecules that could find applications in biology in, for example, fluorescence microscopy or biomolecule quantification.

Synthesis and antitumor activity of 1-substituted 1,2,3-triazole-mollugin derivatives

A new series of mollugin-1,2,3-triazole derivatives were synthesized using a copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of corresponding O-propargylated mollugin with aryl azides. All the compounds were evaluated for their cytotoxicity on five human cancer cell lines (HL-60, A549, SMMC-7721, SW480, and MCF-7) using MTS assays. Among the synthesized series, most of them showed cytotoxicity and most of all, compounds 14 and 17 exhibited significant cytotoxicity of all five cancer cell lines.

Synthesis, characterization and antibacterial activity of the thioether linked 1,2,3-triazoles

A green synthetic approach for the expedite construction of thirty six thioether linked 1,2,3-triazoles was carried out using Cellulose supported CuI nanoparticles in water. The structure of synthesized triazoles was explicated by spectroscopic techniques