128656-57-5

Upstream product

• 57651-44-2 (S)-(-)-3-(2,2,4-trimethyl-1,3-dioxolan-4-yl)propan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 128549-25-7 (S)-(-)-2-(benzyloxy)-2-methyl-4-penten-1-ol 
• 128549-13-3 methyl 2-(benzyloxy)-2-methyl-4-pentenoate 
• 128549-26-8 (S)-2-(benzyloxy)-2-methylpentane-1,5-diol 
• 128549-20-2 (S)-2-Benzyloxy-2-methyl-pent-4-enoic acid 
• 62696-36-0 2-hydroxy-2-methylpent-4-enoic acid methyl ester 
• 136055-42-0 (S)-5-t-Butyldimethylsiloxymethyl-4,5-dihydro-5-methylfuran-2(3H)-one 
• 57624-95-0 (S)-2-methyl-1,2,5-pentanetriol 
• 21461-89-2 (S)-(-)-tetrahydro-2-methyl-5-oxo-2-furancarboxylic acid 

Downstream Products

• 82182-39-6 Toluene-4-sulfonic acid (R)-2-[(3S,8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5-((S)-2,2,4-trimethyl-[1,3]dioxolan-4-yl)-pentyl ester 
• 42737-59-7 25(S),26-Dihydroxyvitamin D₃ 
• 56009-11-1 (1R,3aS,7aR)-1-((1R,5S)-1,5-Dimethyl-5,6-bis-trimethylsilanyloxy-hexyl)-7a-methyl-4-[2-[(S)-2-methylene-5-trimethylsilanyloxy-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-octahydro-indene 

Relevant academic research and scientific papers

Asymmetric Construction of α,α-Disubstituted Cyclobutanones - Enantioselective Total Synthesis of (-)-Frontalin

Novel access to the chiral, α,α-disubstituted ketone 2-hydroxymethyl-2-methylcyclobutanone was developed, leading to an enantioselective total synthesis of (-)-frontalin, an aggregating pheromone of bark beetles.

Enzymatic Preparation of Enantiomerically Enriched Tertiary α-Benzyloxy Acid Esters. Application to the Synthesis of (S)-(-)-Frontalin

Enzymatic preparation of enantiomerically enriched tertiary α-benzyloxy acid esters is described.Enantioselective hydrolysis of the racemic esters of the formula by lipase OF (from Candida cylindracea, Meito Sangyo Co.) was succes