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(R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid is a chemical compound that belongs to the class of aziridine-containing compounds. It is a carboxylic acid derivative, with a tert-butoxycarbonyl group attached to the aziridine ring. (R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid possesses unique reactivity due to the presence of the aziridine ring and the carboxylic acid functionality, making it a versatile building block in organic synthesis and medicinal chemistry.

1286768-92-0

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1286768-92-0 Usage

Uses

Used in Organic Synthesis:
(R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid is used as a building block for the synthesis of various bioactive molecules. Its reactivity and structural features enable the formation of diverse chemical compounds, contributing to the development of new organic compounds with potential applications in various fields.
Used in Medicinal Chemistry:
In the pharmaceutical industry, (R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid is used as a key intermediate for the preparation of bioactive molecules. Its unique structure and reactivity allow for the synthesis of novel drug candidates with potential therapeutic effects.
Used in Peptide and Protein-based Molecules:
(R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid is used as a component in the design and synthesis of peptide and protein-based molecules. Its carboxylic acid functionality allows for its incorporation into these biomolecules, expanding its potential utility in drug discovery and development.
Used in Drug Discovery and Development:
(R)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid is employed as a valuable intermediate in the development of new drugs. Its unique properties and reactivity make it a promising candidate for the synthesis of innovative pharmaceutical compounds with potential therapeutic benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 1286768-92-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,6,7,6 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1286768-92:
(9*1)+(8*2)+(7*8)+(6*6)+(5*7)+(4*6)+(3*8)+(2*9)+(1*2)=220
220 % 10 = 0
So 1286768-92-0 is a valid CAS Registry Number.

1286768-92-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-1-[(2-methylpropan-2-yl)oxycarbonyl]aziridine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1286768-92-0 SDS

1286768-92-0Relevant academic research and scientific papers

Polybasic nitrogen heterocyclic non-natural chiral amino acid and synthesis method thereof

-

, (2018/11/22)

The invention relates to a polybasic nitrogen heterocyclic non-natural chiral amino acid and a synthesis method thereof. The amino acid can be applied to molecule building for antibiotic synthesis. According to the synthesis method, 2-aminodiethyl malonate and halogenated alkanes carry out substitution reactions, cyclization reactions, and decarboxylation reactions, and the reaction products are split to obtain the polybasic nitrogen heterocyclic non-natural chiral amino acid. The provided novel synthesis method has the advantages of simple synthesis route, low cost, convenient operation, andeasiness for commercial production, the chiral purity of obtained products is high, and the application prospect is good.

MELANOCORTIN RECEPTOR AGONISTS

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Page/Page column 49, (2010/02/11)

The present invention relates a compound of formula 1, and pharmaceutically acceptable salt, hydrate, solvate, or isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.

Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis

Baldwin, Jack E.,Farthing, Christopher N.,Russell, Andrew T.,Schofield, Christopher J.,Spivey, Alan C.

, p. 3761 - 3764 (2007/10/03)

(S)-tert-Butyl-N-tert-butoxycarbonylaziridine-2-carboxylate and (S)-tert-butyl-N-tert-butoxycarbonylaziridine-2-carboxamide were synthesised and found to react with copper 'catalysed' Grignard reagents to give protected α-amino acids in moderate to good yields.

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