1286783-65-0Relevant academic research and scientific papers
Highly Z -selective asymmetric 1,4-addition reaction of 5 H -oxazol-4-ones with alkynyl carbonyl compounds catalyzed by chiral guanidines
Misaki, Tomonori,Kawano, Kei,Sugimura, Takashi
supporting information; experimental part, p. 5695 - 5697 (2011/06/18)
An asymmetric 1,4-addition reaction of 5H-oxazol-4-ones with alkynyl carbonyl compounds was developed, and, for the first time, high enantiomeric and geometric control was achieved to afford the thermodynamically unstable Z-isomer predominantly using chir
