1286796-28-8

Upstream product

• 107-19-7 propargyl alcohol 
• 75-05-8 acetonitrile 
• 2783-28-0 4-tert-butylphenylethylene oxide 
• 2181-42-2 trimethylsulphonium iodide 
• 1286796-26-6 2-(4-tert-butylphenyl)prop-2-en-1-yl methyl carbonate 

Downstream Products

• 1286796-27-7 1-tert-butyl-4-(3-fluoroprop-1-en-2-yl)benzene 
• 910487-17-1 2-(4-tert-butylphenyl)prop-2-en-1-yl acetate 
• 1286796-55-1 2-(4-tert-butylphenyl)prop-2-en-1-yl benzoate 
• 1286796-56-2 2-(4-tert-butylphenyl)prop-2-en-1-yl 4-nitrobenzoate 
• 1286796-26-6 2-(4-tert-butylphenyl)prop-2-en-1-yl methyl carbonate 
• 1286796-54-0 2-(4-tert-butylphenyl)prop-2-en-1-yl trifluoroacetate 
• 1507347-51-4 2-(4-(tert-butyl)phenyl)-N,N-diethylacrylamide 

Relevant academic research and scientific papers

N-BuLi/LiCH2CN-mediated one-carbon homologation of aryl epoxides into conjugated allyl alcohols

A series of styrene oxides in the presence of a 1:1 mixture of n-butyllithium (n-BuLi) and lithioacetonitrile (LiCH2CN) in THF are converted into one-carbon homologated allyl alcohols in an unusual regioselective manner.

Regioselective ring-opening α-methylenation of aryl epoxides to conjugated allyl alcohols utilizing n-BuLi and Me2S=CH2 reagents

In the presence of a mixture of n-BuLi and Me2SCH2 reagents, aryl epoxides underwent a novel ring-opening α-methylenation providing conjugated allyl alcohols with an unusual regioselective pattern.

Palladium-catalyzed allylic fluorination

Mild and rapid: The title reaction is presented and its applicability to 18F radiolabeling is demonstrated (see scheme; TBAF=tetra-n- butylammonium fluoride, THF=tetrahydrofuran, dba=dibenzylideneacetone). The use of p-nitrobenzoate as the leaving group is significant to the success of this catalytic organometallic fluorination process. A range of allylic fluorides were synthesized by this method. Copyright